Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DHX15 Is a Coreceptor for RLR Signaling That Promotes Antiviral Defense Against RNA Virus Infection

15 May 2019

Abstract excerpt

RNA helicases play an important role in the response to microbial infection. Retinoic acid inducible gene-I (RIG-I) and members of the RIG-I-like receptor (RLR) family of helicases function as cytoplasmic pattern recognition receptors (PRRs) whose actions are essential for recognition of RNA viruses. RIG-I association with pathogen-associated molecular patterns (PAMPs) within viral RNA leads to its activation and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to interferon and immune responses
Share to RNA Research and Splicing
Share to Viral Infections and Vectors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 31090472
DOI: 10.1089/jir.2018.0163

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DHX15 Is a Coreceptor for RLR Signaling That Promotes Antiviral Defense Against RNA Virus InfectionPMID 31090472Read ↗

The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses.Semantic proximity Read ↗

DDX RNA helicases: key players in cellular homeostasis and innate antiviral immunitySemantic proximity Read ↗

DDX50 is a viral restriction factor that enhances TRIF-dependent IRF3 activationSemantic proximity Read ↗

DDX50 Is a Viral Restriction Factor That Enhances IRF3 ActivationSemantic proximity Read ↗

DDX19 Inhibits Type I Interferon Production by Disrupting TBK1-IKKε-IRF3 Interactions and Promoting TBK1 and IKKε DegradationSemantic proximity Read ↗

Toward a crystal-clear view of the viral RNA sensing and response by RIG-I-like receptorsSemantic proximity Read ↗

Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate ImmunitySemantic proximity Read ↗

Discrimination of cytosolic self and non-self RNA by RIG-I-like receptorsSemantic proximity Read ↗

Distinct RIG-I and MDA5 Signaling by RNA Viruses in Innate ImmunitySemantic proximity Read ↗

Y RNAs are conserved endogenous RIG-I ligands across RNA virus infection and are targeted by HIV-1Semantic proximity Read ↗

Origin and evolution of the RIG-I like RNA helicase gene familySemantic proximity Read ↗

DDX5 and its associated lncRNA Rmrp modulate TH17 cell effector functions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.