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New insights into the ORF2 capsid protein, a key player of the hepatitis E virus lifecycle

18 Apr 2019

Abstract excerpt

Hepatitis E Virus (HEV) genome encodes three proteins including the ORF2 capsid protein. Recently, we demonstrated that HEV produces three different forms of ORF2: (i) the ORF2i form (infectious ORF2) which is the component of infectious particles, (ii) the secreted ORF2g (glycosylated ORF2) and ORF2c (cleaved ORF2) forms that are not associated with infectious particles, but are the major antigens in...

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PMID: 31000788
DOI: 10.1038/s41598-019-42737-2

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