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Article

Progress in the Production of Virus-Like Particles for Vaccination against Hepatitis E Virus

30 Jul 2020

Abstract excerpt

Hepatitis E virus (HEV), a pathogen that causes acute viral hepatitis, is a small icosahedral, quasi-enveloped, positive ssRNA virus. Its genome has three open reading frames (ORFs), with ORF1 and ORF3 encoding for nonstructural and regulatory proteins, respectively, while ORF2 is translated into the structural, capsid protein. ORF2 is most widely used for vaccine development in viral hepatitis. Hepatitis E...

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PMID: 32751441
DOI: 10.3390/v12080826

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