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Article

Next-generation sequencing analysis of the human T-cell and B-cell receptor repertoire diversity before and after hepatitis B vaccination

4 Apr 2019

Abstract excerpt

The hepatitis B (HB) vaccine effectively prevents the incidence of hepatitis B virus (HBV) infection. However, vaccine failure occurs in 5-10% of the recipients. The precise mechanisms leading to responsiveness to the HB vaccine are poorly understood. High-throughput sequencing (HTS) may help clarify the immune response to the HB vaccine, so we applied this method to investigate whether the HB vaccine induced a...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30945971
DOI: 10.1080/21645515.2019.1600987

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