Article
A genome-wide association study identifies polymorphisms in the HLA-DR region associated with non-response to hepatitis B vaccination in Chinese Han populations.
Human molecular genetics - 15 Apr 2014
Pan Liping, Zhang Li, Zhang Wei, Wu Xiaopan, Li Yuanfeng, Yan Bingyu, Zhu Xilin, Liu Xing, Yang Chao, Xu Jianfeng, Zhou Gangqiao, Xu Aiqiang, Li Hui, Liu Ying
Abstract excerpt
Vaccination against hepatitis B virus is an effective and routine practice that can prevent infection. However, 5-10% of healthy adults fail to produce protective levels of antibody against the hepatitis B vaccination. It has been reported that host genetic variants might affect the immune response to hepatitis B vaccination. Here, we reported a genome-wide association study in a Chinese Han population consisting...
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