Genome-Wide Multiple Sclerosis Association Data and Coagulation

Abstract excerpt

The emerging concept of a crosstalk between hemostasis, inflammation and immune system prompt recent works on coagulation cascade in multiple sclerosis (MS). Studies on MS pathology identified several coagulation factors since the beginning of the disease pathophysiology: fibrin deposition with breakdown of blood brain barrier, and coagulation factors within active plaques may exert pathogenic role, especially...

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