Article
Genetic Epidemiology of Breast Cancer in Latin America.
Genes - 18 Feb 2019
Zavala Valentina A, Serrano-Gomez Silvia J, Dutil Julie, Fejerman Laura
Abstract excerpt
The last 10 years witnessed an acceleration of our understanding of what genetic factors underpin the risk of breast cancer. Rare high- and moderate-penetrance variants such as those in the BRCA genes account for a small proportion of the familial risk of breast cancer. Low-penetrance alleles are expected to underlie the remaining heritability. By now, there are about 180 genetic polymorphisms that are associated...
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