Article
The emerging landscape of breast cancer susceptibility.
Nature genetics - 1 Jan 2008
Stratton Michael R, Rahman Nazneen
Abstract excerpt
The genetic basis of inherited predisposition to breast cancer has been assiduously investigated for the past two decades and has been the subject of several recent discoveries. Three reasonably well-defined classes of breast cancer susceptibility alleles with different levels of risk and prevalence in the population have become apparent: rare high-penetrance alleles, rare moderate-penetrance alleles and common...
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