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Article

Mutations present in a low-passage Zika virus isolate result in attenuated pathogenesis in mice

9 Feb 2019

Abstract excerpt

Zika virus (ZIKV) infection can result in neurological disorders including Congenital Zika Syndrome in infants exposed to the virus in utero. Pregnant women can be infected by mosquito bite as well as by sexual transmission from infected men. Herein, the variants of ZIKV within the male reproductive tract and ejaculates were assessed in inoculated mice. We identified two non-synonymous variants at positions...

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PMID: 30763872
DOI: 10.1016/j.virol.2019.02.004

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