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Duration of seminal Zika viral RNA shedding in immunocompetent mice inoculated with Asian and African genotype viruses

20 Jun 2019

Abstract excerpt

Prior to the emergence of Asian genotype Zika virus (ZIKV) in the Western hemisphere, sexual transmission in humans was documented. Sexual transmission by African genotype ZIKVs has not been assessed in laboratory animal models, due to rapid and high mortality rates of immunodeficient mice following inoculation. To overcome these limitations, immunocompetent C57Bl/6 mice were used to longitudinally assess Asian...

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PMID: 31254742
DOI: 10.1016/j.virol.2019.06.010

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