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Room Temperature Detection of Plasma Epstein–Barr Virus DNA with CRISPR–Cas13

12 Feb 2019

Abstract excerpt

To the Editor: Detection of plasma Epstein–Barr virus (EBV)1 DNA is useful for screening and monitoring nasopharyngeal carcinoma (NPC) and other EBV-associated diseases (1–3). However, quantitative PCR requires complex and expensive instrumentation, restricting its use in point-of-care testing and remote regions (4). Thus, a simple, portable, and inexpensive EBV DNA detection assay is needed. Prokaryotic...

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PMID: 30755401
DOI: 10.1373/clinchem.2018.299347

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