Characterization of the housekeeping sortase from the human pathogen Propionibacterium acnes: first investigation of a class F sortase

Abstract excerpt

Abstract Sortase enzymes play an important role in Gram-positive bacteria. They are responsible for the covalent attachment of proteins to the surface of the bacteria and perform this task via a highly sequence-specific transpeptidation reaction. Since these immobilized proteins are often involved in pathogenicity of Gram-positive bacteria, characterization of this type of enzyme is also of medical relevance....

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biochemical and Structural Characterization
• Share to Streptococcal Infections and Treatments