Article

Daphnoretin as a Potent Sortase A Inhibitor Effectively Disarms Drug-Resistant Staphylococcus aureus Infections

2025-11-03

Abstract excerpt

<title>Abstract</title> <p> The rapid spread of drug-resistant <italic>Staphylococcus aureus</italic> ( <italic>S. aureus</italic> ) has severely undermined the efficacy of existing antibiotics, highlighting the urgent need to explore novel antiinfective strategies to address this global public health challenge. Sortase A (SrtA) is a critical virulence factor of <italic>S. aureus</italic> that covalently a...

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Literature Corpus work: 970cf6fb-9de2-5e57-83c8-0332d09e3ea7
DOI: 10.21203/rs.3.rs-7820020/v1

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