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Yeast to Study Human Purine Metabolism Diseases

17 Jan 2019

Abstract excerpt

Purine nucleotides are involved in a multitude of cellular processes, and the dysfunction of purine metabolism has drastic physiological and pathological consequences. Accordingly, several genetic disorders associated with defective purine metabolism have been reported. The etiology of these diseases is poorly understood and simple model organisms, such as yeast, have proved valuable to provide a more...

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PMID: 30658520
DOI: 10.3390/cells8010067

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