Article
Contemporary, yeast-based approaches to understanding human genetic variation.
Current opinion in genetics & development - 1 Dec 2013
Dunham Maitreya J, Fowler Douglas M
Abstract excerpt
Determining how genetic variation contributes to human health and disease is a critical challenge. As one of the most genetically tractable model organisms, yeast has played a central role in meeting this challenge. The advent of new technologies, including high-throughput DNA sequencing and synthesis, proteomics, and computational methods, has vastly increased the power of yeast-based approaches to determine the...
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