Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases.

Genes - 20 Feb 2021

Ceccatelli Berti Camilla, di Punzio Giulia, Dallabona Cristina, Baruffini Enrico, Goffrini Paola, Lodi Tiziana, Donnini Claudia

Abstract excerpt

The increasing application of next generation sequencing approaches to the analysis of human exome and whole genome data has enabled the identification of novel variants and new genes involved in mitochondrial diseases. The ability of surviving in the absence of oxidative phosphorylation (OXPHOS) and mitochondrial genome makes the yeast Saccharomyces cerevisiae an excellent model system for investigating the role...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Nucleus
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Profiling

Share to Genes, Mitochondrial

Share to Mitochondria

Share to Mitochondrial Diseases

Share to Oxidative Phosphorylation

Share to Yeasts

Source

Open in PubMed Open full text

Identifiers

PMID: 33672627
DOI: 10.3390/genes12020300
PMCID: PMC7924180

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases.PMID 33672627Read ↗

The power of yeast to model diseases of the powerhouse of the cell.Semantic proximity Read ↗

Saccharomyces cerevisiae as a Tool for Studying Mutations in Nuclear Genes Involved in Diseases Caused by Mitochondrial DNA Instability.Semantic proximity Read ↗

Creation of Yeast Models for Evaluating the Pathogenicity of Mutations in the Human Mitochondrial Gene MT-ATP6 and Discovering Therapeutic Molecules.Semantic proximity Read ↗

Yeast as a Tool to Understand the Significance of Human Disease-Associated Gene Variants.Semantic proximity Read ↗

Mitochondrial disorders.Semantic proximity Read ↗

Homo cerevisiae-Leveraging Yeast for Investigating Protein-Protein Interactions and Their Role in Human Disease.Semantic proximity Read ↗

Contemporary, yeast-based approaches to understanding human genetic variation.Semantic proximity Read ↗

Probing the pathogenicity of patient-derived variants of MT-ATP6 in yeast.Semantic proximity Read ↗

Respiratory complex III dysfunction in humans and the use of yeast as a model organism to study mitochondrial myopathy and associated diseases.Semantic proximity Read ↗

Yeast to Study Human Purine Metabolism DiseasesSemantic proximity Read ↗

Mitochondrial Aminoacyl-tRNA Synthetase and Disease: The Yeast Contribution for Functional Analysis of Novel Variants.Semantic proximity Read ↗

The Saccharomyces cerevisiae mitochondrial DNA polymerase and its contribution to the knowledge about human POLG-related disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.