[Saccharomyces cerevisiae: an efficient tool and model system for anticancer research].

Abstract excerpt

The major mechanisms of cell function, such as metabolic pathways, DNA repair and cell cycle control have been conserved throughout DNA evolution from yeast to human, despite the former lacks cancer-related features. The S. cerevisiae genome has been entirely sequenced and not only reveals sequence similarity to the human, but a number of proteins also have a conserved function. Owing to its genetic features,...

Topics

• Antineoplastic Agents
• Drug Screening Assays, Antitumor
• Enzyme Inhibitors
• Phenotype
• Prodrugs
• Pyrimidines
• Saccharomyces cerevisiae