Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Yeast as a Tool to Understand the Significance of Human Disease-Associated Gene Variants.

Genes - 24 Aug 2021

Cervelli Tiziana, Galli Alvaro

Abstract excerpt

At present, the great challenge in human genetics is to provide significance to the growing amount of human disease-associated gene variants identified by next generation DNA sequencing technologies. Increasing evidences suggest that model organisms are of pivotal importance to addressing this issue. Due to its genetic tractability, the yeast Saccharomyces cerevisiae represents a valuable model organism for...

Topics

Genetic Diseases, Inborn
Genome-Wide Association Study
Humans
Mutation
Saccharomyces cerevisiae
Saccharomyces cerevisiae Proteins

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 34573285
DOI: 10.3390/genes12091303
PMCID: PMC8465565

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-34573285-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Yeast as a Tool to Understand the Significance of Human Disease-Associated Gene Variants.PMID 34573285Read ↗

Homo cerevisiae-Leveraging Yeast for Investigating Protein-Protein Interactions and Their Role in Human Disease.Semantic proximity Read ↗

Contemporary, yeast-based approaches to understanding human genetic variation.Semantic proximity Read ↗

Protein-protein interactions and disease: use of S. cerevisiae as a model system.Semantic proximity Read ↗

The Power of Yeast in Modelling Human Nuclear Mutations Associated with Mitochondrial Diseases.Semantic proximity Read ↗

Humanized yeast to model human biology, disease and evolution.Semantic proximity Read ↗

New insights into cancer‐related proteins provided by the yeast modelSemantic proximity Read ↗

Yeast to Study Human Purine Metabolism DiseasesSemantic proximity Read ↗

Saccharomyces genome database informs human biology.Semantic proximity Read ↗

Saccharomyces cerevisiae as a model system to study the response to anticancer agents.Semantic proximity Read ↗

High-throughput approaches to functional characterization of genetic variation in yeast.Semantic proximity Read ↗

Saccharomyces cerevisiae as a Tool for Studying Mutations in Nuclear Genes Involved in Diseases Caused by Mitochondrial DNA Instability.Semantic proximity Read ↗

A molecular approach to understanding human sterol metabolism using yeast genetics.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.