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Article

Sex-related DNA methylation differences in B cell chronic lymphocytic leukemia

7 Jan 2019

Abstract excerpt

BACKGROUND: Men are at higher risk of developing chronic lymphocytic leukemia (CLL) than women. DNA methylation has been shown to play important roles in a number of cancers. There are differences in the DNA methylation pattern between men and women. In this study, we investigated whether this contributes to the sex-related difference of B cell CLL risk. METHODS: B cells from 48 CLL patients (29 female patients...

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Share to Chronic Lymphocytic Leukemia Research
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PMID: 30616686
DOI: 10.1186/s13293-018-0213-7

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