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Article

Oncogenic CagA promotes gastric cancer risk via activating ERK signaling pathways: a nested case-control study.

PloS one - 1 Jan 2011

Yang Jae Jeong, Cho Lisa Y, Ma Seung Hyun, Ko Kwang-Pil, Shin Aesun, Choi Bo Youl, Han Dong Soo, Song Kyu Sang, Kim Yong Sung, Chang Soung-Hoon, Shin Hai-Rim, Kang Daehee, Yoo Keun-Young, Park Sue K

Abstract excerpt

BACKGROUND: CagA cellular interaction via activation of the ERK signaling pathway may be a starting point in the development of gastric cancer. This study aimed to evaluate whether genes involved in ERK downstream signaling pathways activated by CagA are susceptible genetic markers for gastric cancer. METHODS: In the discovery phase, a total of 580 SNPs within +/-5 kbp of 30 candidate genes were genotyped to...

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Identifiers

PMID: 21698158
DOI: 10.1371/journal.pone.0021155
PMCID: PMC3116873

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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