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Article

Genetic identification of Ly75 as a novel quantitative trait gene for resistance to obesity in mice

29 Nov 2018

Abstract excerpt

Identification of causal quantitative trait genes (QTGs) governing obesity is challenging. We previously revealed that the lymphocyte antigen 75 (Ly75) gene with an immune function is a putative QTG for Pbwg1.5, a quantitative trait locus (QTL) for resistance to obesity found from wild mice (Mus musculus castaneus). The objective of this study was to identify a true QTG for Pbwg1.5 by a combined approach of a...

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PMID: 30518881
DOI: 10.1038/s41598-018-36073-0

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