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Article

Using mouse models to dissect the genetics of obesity.

Trends in genetics : TIG - 1 Jul 2002

Brockmann Gudrun A, Bevova Marianna R

Abstract excerpt

Mice have proved to be powerful models for understanding obesity in humans and farm animals. Single-gene mutants and genetically modified mice have been used successfully to discover genes and pathways that can regulate body weight. For polygenic obesity, the most common pattern of inheritance, many quantitative trait loci (QTLs) have been mapped in crosses between selected and inbred mouse lines. Most QTL...

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PMID: 12127777
DOI: 10.1016/s0168-9525(02)02703-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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