Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Profiling of Methylglyoxal Blood Metabolism and Advanced Glycation End-Product Proteome Using a Chemical Probe

3 Dec 2018

Abstract excerpt

Methylglyoxal (MG) is quantitatively the most important precursor to advanced glycation end-products (AGEs), and evidence is accumulating that it is also a causally linked to diabetes and aging related diseases. Living systems primarily reside on the glyoxalase system to detoxify MG into benign d-lactate. The flux to either glycation or detoxification, accordingly, is a key parameter for how well a system handles...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Advanced Glycation End Products research
Share to Alzheimer's disease research and treatments
Share to Peroxisome Proliferator-Activated Receptors

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30508371
DOI: 10.1021/acschembio.8b00732

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Profiling of Methylglyoxal Blood Metabolism and Advanced Glycation End-Product Proteome Using a Chemical ProbePMID 30508371Read ↗

Glyoxylate, a new marker metabolite of type 2 diabetes.Semantic proximity Read ↗

A Chemical Mechanistic Path Leads the Way to Cellular ArgpyrimidineSemantic proximity Read ↗

Methylglyoxal in Cardiometabolic Disorders – Routes Leading to Pathology – Counterbalanced by Treatment StrategiesSemantic proximity Read ↗

Molecular Assessment of Methylglyoxal-Induced Toxicity and Therapeutic Approaches in Various Diseases: Exploring the Interplay with the Glyoxalase SystemSemantic proximity Read ↗

Glyoxalase activity in human erythrocytes and mouse lymphoma, liver and brain probed with hyperpolarized 13C-methylglyoxalSemantic proximity Read ↗

Discovery of Glycation-Derived Crosslinks at ArginineSemantic proximity Read ↗

Non-enzymatic RNA Glycation is a Metabolic Sensor of Cellular StressSemantic proximity Read ↗

A Cyclic Arginine Adduct Eclipses Carboxymethylation as the Primary Glyoxal-Derived Advanced Glycation End-ProductSemantic proximity Read ↗

The Human Glyoxalase Gene Family in Health and DiseaseSemantic proximity Read ↗

Arginine metabolism is a biomarker of red blood cell and human agingSemantic proximity Read ↗

Methylglyoxal Drives a Distinct, Nonclassical Macrophage Activation Status.Semantic proximity Read ↗

Proteomic analysis of red blood cells and the potential for the clinic: what have we learned so far?Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.