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The Human Glyoxalase Gene Family in Health and Disease

1 Sept 2022

Abstract excerpt

The glyoxalase gene family consists of six structurally and functionally diverse enzymes with broad roles in metabolism. The common feature that defines this family is based on structural motifs that coordinate divalent cations which are required for activity. These family members have been implicated in a variety of physiological processes, including amino-acid metabolism (4-hydroxyphenylpyruvate dioxygenase;...

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PMID: 36048613
DOI: 10.1021/acs.chemrestox.2c00182

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