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Article

Glyoxylate, a new marker metabolite of type 2 diabetes.

Journal of diabetes research - 1 Jan 2014

Nikiforova Victoria J, Giesbertz Pieter, Wiemer Jan, Bethan Bianca, Looser Ralf, Liebenberg Volker, Ruiz Noppinger Patricia, Daniel Hannelore, Rein Dietrich

Abstract excerpt

Type 2 diabetes (T2D) is characterized by a variety of metabolic impairments that are closely linked to nonenzymatic glycation reactions of proteins and peptides resulting in advanced glycation end-products (AGEs). Reactive aldehydes derived from sugars play an important role in the generation of AGEs. Using metabolite profiling to characterize human plasma from diabetic versus nondiabetic subjects we observed in...

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Identifiers

PMID: 25525609
DOI: 10.1155/2014/685204
PMCID: PMC4265698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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