Article
Glyoxylate, a new marker metabolite of type 2 diabetes.
Journal of diabetes research - 1 Jan 2014
Nikiforova Victoria J, Giesbertz Pieter, Wiemer Jan, Bethan Bianca, Looser Ralf, Liebenberg Volker, Ruiz Noppinger Patricia, Daniel Hannelore, Rein Dietrich
Abstract excerpt
Type 2 diabetes (T2D) is characterized by a variety of metabolic impairments that are closely linked to nonenzymatic glycation reactions of proteins and peptides resulting in advanced glycation end-products (AGEs). Reactive aldehydes derived from sugars play an important role in the generation of...
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