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Article

Impact of PCSK9 loss-of-function genotype on 1-year mortality and recurrent infection in sepsis survivors

23 Nov 2018

Abstract excerpt

BACKGROUND: Reduced activity of proprotein convertase subtilisin/kexin type 9 (PCSK9) has been associated with decreased short-term death in patients with septic shock. Whether PCSK9 genotype influences long-term outcomes in sepsis survivors is unknown. METHODS: We evaluated the impact of PCSK9 loss-of-function (LOF) genotype on both 1-year mortality and infection-related readmission (IRR) after an index sepsis...

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PMID: 30473376
DOI: 10.1016/j.ebiom.2018.11.032

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