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Article

Potential roles of IL-1 subfamily members in glycolysis in disease

16 Nov 2018

Abstract excerpt

The interleukin-(IL)-1 subfamily consists of IL-1α, IL-1β, IL-1 receptor antagonist IL-1Ra and IL-33. These cytokines are the main members of the IL-1 family and have been widely recognized as having significant roles in pro-inflammatory and immunomodulatory actions. Mounting evidence has revealed that these cytokines also play key roles in the regulation of glycolysis, which is an important metabolic pathway in...

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PMID: 30470512
DOI: 10.1016/j.cytogfr.2018.11.001

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