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Article

CTCs‐derived xenograft development in a triple negative breast cancer case

19 Nov 2018

Abstract excerpt

Triple-negative breast cancer (TNBC) is characterized by high rates of metastasis and no available molecular targets. CTCs derived xenografts (CDX) have demonstrated to be a promising tool for understanding cancer biology. In our study, a CDX from a TNBC patient was developed for the first time. After CDX characterization, WNT signaling was found as the main mechanism related with this tumor biology and potential...

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PMID: 30450632
DOI: 10.1002/ijc.32001

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