Site-directed mutation affecting polyomavirus capsid self-assembly in vitro.

doi:10.1038/329086a0

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Article

Site-directed mutation affecting polyomavirus capsid self-assembly in vitro.

Nature - 1 Jan 2000

Garcea R L, Salunke D M, Caspar D L

Abstract excerpt

Nonequivalent bonding of identical protein subunits occurs in the polyomavirus capsid were identical pentameric capsomeres occupy both hexavalent and pentavalent positions in the icosahedral surface lattice. The polyomavirus major capsid protein VP1, purified after expression of the recombinant g...

Topics

Amino Acid Sequence
Base Sequence
Capsid
Escherichia coli
Macromolecular Substances
Microscopy, Electron
Mutation
Polyomavirus
Protein Processing, Post-Translational

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