Article
HLA-DRB1*04 and DRB1*10 are associated with resistance and susceptibility, respectively, in Brazilian and Vietnamese leprosy patients.
Genes and immunity - 1 Jun 2007
Vanderborght P R, Pacheco A G, Moraes M E, Antoni G, Romero M, Verville A, Thai V H, Huong N T, Ba N N, Schurr E, Sarno E N, Moraes M O
Abstract excerpt
The host genetic background has been considered one of the factors that influence leprosy outcome, a chronic infectious disease caused by Mycobacterium leprae. Genome scans demonstrated that the 6p21 region is associated with leprosy and a substantial number of population-based studies analyzing...
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