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Vitexin compound 1, a novel extraction from a Chinese herb, suppresses melanoma cell growth through DNA damage by increasing ROS levels

6 Nov 2018

Abstract excerpt

BACKGROUND: Vitex negundo L (Verbenaceae) is an aromatic shrub that is abundant in Asian countries. A series of compounds from Vitex negundo have been used in traditional Chinese medicine for the treatment of various diseases. Cutaneous melanoma is one of the most aggressive malignancies. A significant feature of melanoma is its resistance to traditional chemotherapy and radiotherapy; therefore, there is an...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30400954
DOI: 10.1186/s13046-018-0897-x

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