Article

Physachenolide C induces complete regression of established murine melanoma tumors via apoptosis and cell cycle arrest

2021-05-28

Abstract excerpt

Melanoma is an aggressive skin cancer that metastasizes to other organs. While immune checkpoint blockade with anti-PD-1 has transformed the treatment of advanced melanoma, many melanoma patients fail to respond to anti-PD-1 therapy or develop acquired resistance. Thus, effective treatment of melanoma still represents an unmet clinical need. Our prior studies support the anti-cancer activity of the 17β-hydroxywith...

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Literature Corpus work: 14da9690-14d7-5f46-916c-dcb29f3ffa4a
DOI: 10.1101/2021.05.27.445710

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