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The Landscape and Implications of Chimeric RNAs in Cervical Cancer

31 Oct 2018

Abstract excerpt

BACKGROUND: Gene fusions and fusion products have been proven to be ideal biomarkers and drug targets for cancer. Even though a comprehensive study of cervical cancer has been conducted as part of the Cancer Genome Atlas (TCGA) project, few recurrent gene fusions have been found, and none above 3% of frequency. METHODS: We believe that chimeric fusion RNAs generated by intergenic splicing represent a new...

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PMID: 30389505
DOI: 10.1016/j.ebiom.2018.10.059

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