Article
Characterization of fusion genes in common and rare epithelial ovarian cancer histologic subtypes.
Oncotarget - 18 Jul 2017
Earp Madalene A, Raghavan Rama, Li Qian, Dai Junqiang, Winham Stacey J, Cunningham Julie M, Natanzon Yanina, Kalli Kimberly R, Hou Xiaonan, Weroha S John, Haluska Paul, Lawrenson Kate, Gayther Simon A, Wang Chen, Goode Ellen L, Fridley Brooke L
Abstract excerpt
Gene fusions play a critical role in some cancers and can serve as important clinical targets. In epithelial ovarian cancer (EOC), the contribution of fusions, especially by histological type, is unclear. We therefore screened for recurrent fusions in a histologically diverse panel of 220 EOCs using RNA sequencing. The Pipeline for RNA-Sequencing Data Analysis (PRADA) was used to identify fusions and allow for...
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