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Influenza A Virus Superinfection Potential Is Regulated by Viral Genomic Heterogeneity

29 Oct 2018

Abstract excerpt

Superinfection, the sequential infection of a single cell by two or more virions, plays an important role in determining the replicative and evolutionary potential of influenza A virus (IAV) populations. The specific mechanisms that regulate superinfection during natural infection remain poorly understood. Here, we show that superinfection susceptibility is determined by the total number of viral genes expressed...

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PMID: 30377278
DOI: 10.1128/mbio.01761-18

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