Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progression

23 Oct 2018

Abstract excerpt

INTRODUCTION: Brain-Derived Neurotrophic Factor (BDNF) and its most common polymorphism Val66Met are known to have a role in Multiple Sclerosis (MS) pathogenesis. Evidence is accumulating that there is an involvement of DNA methylation in the regulation of BDNF expression. The aim of this study was to assess in blood samples of MS patients the correlation between the methylation status of the CpG site near...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related gene regulation
Share to Nerve injury and regeneration
Share to Neurogenetic and Muscular Disorders Research

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 30352103
DOI: 10.1371/journal.pone.0206140

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progressionPMID 30352103Read ↗

BDNF rs6265 Polymorphism and Its Methylation in Patients with Stroke Undergoing Rehabilitation.Semantic proximity Read ↗

The BDNF-Val66Met polymorphism: implications for susceptibility to multiple sclerosis and severity of disease.Semantic proximity Read ↗

BDNF Val66Met polymorphism and brain volumes in multiple sclerosis.Semantic proximity Read ↗

The BDNF Val66Met Polymorphism (rs6265) Modulates Inflammation and Neurodegeneration in the Early Phases of Multiple Sclerosis.Semantic proximity Read ↗

[BDNF gene RS6265 polymorphism in patients with multiple sclerosis of Tomsk region].Semantic proximity Read ↗

Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course.Semantic proximity Read ↗

Interaction between miR-142-3p and BDNF Val/Met Polymorphism Regulates Multiple Sclerosis Severity.Semantic proximity Read ↗

Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.Semantic proximity Read ↗

Investigating the role of brain-derived neurotrophic factor in relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

BDNF DNA methylation changes as a biomarker of psychiatric disorders: literature review and open access database analysis.Semantic proximity Read ↗

The Effects of The MTHFR 677C>T (Rs1801133) Genetic Variant on Susceptibility and Disability in Multiple Sclerosis Patients are Mediated by Homocysteine But Not Folate LevelsSemantic proximity Read ↗

Expression and methylation of BDNF in the human brain in schizophrenia.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.