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Article

Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course.

Journal of neuroimmunology - 1 Mar 2012

Mero Inger-Lise, Smestad Cathrine, Lie Benedicte A, Lorentzen Åslaug R, Sandvik Leiv, Landrø Nils Inge, Aarseth Jan H, Myhr Kjell-Morten, Celius Elisabeth G, Harbo Hanne F

Abstract excerpt

Brain-derived neurotrophic factor (BDNF) has been proposed a protective role in multiple sclerosis (MS) in several studies. The val(66)met polymorphism alters the function of the BDNF protein, and has along with rs56164415 previously been reported to be associated with MS. We genotyped BDNF SNPs val(66)met and rs56164415 in 2149 Norwegian MS patients and 2747 healthy controls. No association was found for any of...

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Identifiers

PMID: 22341604
DOI: 10.1016/j.jneuroim.2012.01.011

Genes

BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Polymorphisms of the BDNF gene show neither association with multiple sclerosis susceptibility nor clinical course.PMID 22341604Read ↗

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BDNF rs6265 polymorphism methylation in Multiple Sclerosis: A possible marker of disease progressionSemantic proximity Read ↗

BDNF Val66Met polymorphism and brain volumes in multiple sclerosis.Semantic proximity Read ↗

[BDNF gene RS6265 polymorphism in patients with multiple sclerosis of Tomsk region].Semantic proximity Read ↗

Preservation of gray matter volume in multiple sclerosis patients with the Met allele of the rs6265 (Val66Met) SNP of brain-derived neurotrophic factor.Semantic proximity Read ↗

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Association analysis of brain-derived neurotrophic factor Val66Met polymorphisms with Alzheimer's disease and age of onset.Semantic proximity Read ↗

Polymorphism at codon 66 of the brain-derived neurotrophic factor gene is not associated with sporadic Alzheimer's disease.Semantic proximity Read ↗

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