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Article

BDNF rs6265 Polymorphism and Its Methylation in Patients with Stroke Undergoing Rehabilitation.

International journal of molecular sciences - 10 Nov 2020

Santoro Massimo, Siotto Mariacristina, Germanotta Marco, Bray Elisa, Mastrorosa Alessia, Galli Camilla, Papadopoulou Dionysia, Aprile Irene

Abstract excerpt

Brain-Derived Neurotrophic Factor (BDNF) and its rs6265 single nucleotide polymorphism (SNP) play an important role in post-stroke recovery. We investigated the correlation between BDNF rs6265 SNP and recovery outcome, measured by the modified Barthel index, in 49 patients with stroke hospitalized in our rehabilitation center at baseline (T0) and after 30 sessions of rehabilitation treatment (T1); moreover, we...

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Identifiers

PMID: 33182716
DOI: 10.3390/ijms21228438
PMCID: PMC7696026

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