Expression and methylation of BDNF in the human brain in schizophrenia.

doi:10.1080/15622975.2016.1245443

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Article

Expression and methylation of BDNF in the human brain in schizophrenia.

The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry - 1 Aug 2017

Cheah Sern-Yih, McLeay Robert, Wockner Leesa F, Lawford Bruce R, Young Ross McD, Morris Charles P, Voisey Joanne

Abstract excerpt

OBJECTIVES: To examine the combined effect of the BDNF Val66Met (rs6265) polymorphism and BDNF DNA methylation on transcriptional regulation of the BDNF gene. METHODS: DNA methylation profiles were generated for CpG sites proximal to Val66Met, within BDNF promoter I and exon V for prefrontal cortex samples from 25 schizophrenia and 25 control subjects. Val66Met genotypes and BDNF mRNA expression data were...

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PMID: 27712141
DOI: 10.1080/15622975.2016.1245443

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BDNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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