Article
Tissue-Dependent Expression of Bitter Receptor TAS2R38 mRNA.
Chemical senses - 1 Jan 2019
Douglas Jennifer E, Lin Cailu, Mansfield Corrine J, Arayata Charles J, Cowart Beverly J, Spielman Andrew I, Adappa Nithin D, Palmer James N, Cohen Noam A, Reed Danielle R
Abstract excerpt
TAS2R38 is a human bitter receptor gene with a common but inactive allele; people homozygous for the inactive form cannot perceive low concentrations of certain bitter compounds. The frequency of the inactive and active forms of this receptor is nearly equal in many human populations, and heteroz...
Topics
- Adult
- Alleles
- Female
- Gene Expression
- Genotype
- Heterozygote
- Humans
- Male
- Nasal Cavity
- Polymorphism, Single Nucleotide
- RNA, Messenger
- Receptors, G-Protein-Coupled
- Taste
- Tongue
- Taste Receptors, Type 2