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Altered tryptophan metabolism is associated with pediatric multiple sclerosis risk and course

27 Sept 2018

Abstract excerpt

OBJECTIVE: To determine if altered tryptophan (Trp) metabolism is associated with MS risk or disease severity in children. METHODS: Participants with pediatric-onset MS and clinically isolated syndrome (CIS) within 4 years of disease onset and healthy controls underwent collection of serum. Longitudinal disability and processing speed measures and relapse data were collected in cases. Global metabolomics were...

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PMID: 30349856
DOI: 10.1002/acn3.637

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