Article

Integrated multi-omics analysis identifies microbial and metabolic signatures and drivers of CNS autoimmunity

2026-01-09

Abstract excerpt

<h4>ABSTRACT</h4> Multiple sclerosis (MS) is an autoimmune disease of the central nervous system (CNS) driven by genetic and environmental determinants. The gut microbiome of people with MS (pwMS) is distinct and influences disease through immunomodulatory metabolite production. Circulating metabolites are altered in pwMS, but identifying microbial-metabolic drivers remains challenging. We previously showed that...

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Literature Corpus work: 4da84e29-8873-5d66-a3c8-0fe74694da8c
DOI: 10.64898/2026.01.08.698420

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