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Article

Constitutive P2Y2 receptor activity regulates basal lipolysis in human adipocytes

17 Oct 2018

Abstract excerpt

ABSTRACT White adipocytes are key regulators of metabolic homeostasis, which release stored energy as free fatty acids via lipolysis. Adipocytes possess both basal and stimulated lipolytic capacity, but limited information exists regarding the molecular mechanisms that regulate basal lipolysis. Here, we describe a mechanism whereby autocrine purinergic signalling and constitutive P2Y2 receptor activation...

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Share to Adenosine and Purinergic Signaling
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PMID: 30333139
DOI: 10.1242/jcs.221994

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