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Article

CCN proteins as potential actionable targets in scleroderma

17 Oct 2018

Abstract excerpt

Systemic sclerosis (SSc) is a complex autoimmune connective tissue disease combining inflammatory, vasculopathic and fibrotic manifestations. Skin features, which give their name to the disease and are considered as diagnostic as well as prognostic markers, have not been thoroughly investigated in terms of therapeutic targets. CCN proteins (CYR61/CCN1, CTGF/CCN2, NOV/CCN3 and WISP1-2-3 as CCN4-5-6) are a family...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 30329180
DOI: 10.1111/exd.13806

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