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Article

Bioinformatics-integrated screening of systemic sclerosis-specific expressed markers to identify therapeutic targets

30 Mar 2023

Abstract excerpt

Background: Systemic sclerosis (SSc) is a rare autoimmune disease characterized by extensive skin fibrosis. There are no effective treatments due to the severity, multiorgan presentation, and variable outcomes of the disease. Here, integrated bioinformatics was employed to discover tissue-specific expressed hub genes associated with SSc, determine potential competing endogenous RNAs (ceRNA) regulatory networks,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 37063926
DOI: 10.3389/fimmu.2023.1125183

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