Article
Genetics and proteomics in scleroderma.
Current rheumatology reports - 1 Apr 2005
Feghali-Bostwick Carol A
Abstract excerpt
The pathogenesis of systemic sclerosis (SSc; scleroderma) is still enigmatic. Genetic, familial, and twin studies suggest that SSc occurs in genetically susceptible individuals. Recent high-throughput technologies, including gene expression profiling and proteomics, have accelerated the rate of information acquired on possible mechanisms involved in SSc pathogenesis. The potential of the data obtained lies in...
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