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Article

Environmental enrichment has minimal effects on behavior in the Shank3 complete knockout model of autism spectrum disorder.

Brain and behavior - 1 Nov 2018

Hulbert Samuel W, Bey Alexandra L, Jiang Yong-Hui

Abstract excerpt

INTRODUCTION: Several studies have supported the use of enriched environments to prevent the manifestation of ASD-like phenotypes in laboratory rodents. While the translational value of such experiments is unknown, the findings have been relatively consistent across many different models. METHODS: In the current study, we tested the effects of early environmental enrichment on a mouse model of ASD with high...

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PMID: 30317697
DOI: 10.1002/brb3.1107
PMCID: PMC6236244

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