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Article

Arginine reprogramming in ADPKD results in arginine-dependent cystogenesis.

American journal of physiology. Renal physiology - 1 Dec 2018

Trott Josephine F, Hwang Vicki J, Ishimaru Tatsuto, Chmiel Kenneth J, Zhou Julie X, Shim Kyuhwan, Stewart Benjamin J, Mahjoub Moe R, Jen Kuang-Yu, Barupal Dinesh K, Li Xiaogang, Weiss Robert H

Abstract excerpt

Research into metabolic reprogramming in cancer has become commonplace, yet this area of research has only recently come of age in nephrology. In light of the parallels between cancer and autosomal dominant polycystic kidney disease (ADPKD), the latter is currently being studied as a metabolic disease. In clear cell renal cell carcinoma (RCC), which is now considered a metabolic disease, we and others have shown...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 30280600
DOI: 10.1152/ajprenal.00025.2018
PMCID: PMC6336982

Genes

ASS1

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