Article
Alpha kinase 1 controls intestinal inflammation by suppressing the IL-12/Th1 axis
12 Sept 2018
Abstract excerpt
Abstract Inflammatory bowel disease (IBD) are heterogenous disorders of the gastrointestinal tract caused by a spectrum of genetic and environmental factors. In mice, overlapping regions of chromosome 3 have been associated with susceptibility to IBD-like pathology, including a locus called Hiccs. However, the specific gene that controls disease susceptibility remains unknown. Here we identify a Hiccs locus gene,...
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