Article
IFNG +874 A/T is associated with acute lymphoblastic leukemia in Mexican Mestizos.
Cytokine - 1 Nov 2018
González-Quezada Betsy Annel, Flores-Aguilar Hilario, Olaya-Vargas Alberto, Salazar-Rosales Haydee, Pérez-García Martín, Valero-Saldaña Luis Manuel, Acosta-Maldonado Brenda Lizeth, Ovilla-Martínez Roberto, Gorodezky Clara
Abstract excerpt
Acute lymphoblastic leukemia (ALL), the most common type of cancer in children worldwide, has one of the highest incidence rates in Mexico. It is a multifactorial disease and different cytokine single nucleotide polymorphisms (SNP), have been associated with ALL expression. Few studies have been published analyzing IFNG +874 T/A and IL2 -330 G/T in this type of leukemia. These SNPs are involved in high or low...
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